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Test Requirements
 
Title
METHYLMALONIC ACID, SERUM
Specimen Requirement
<p>1 SST/1.0 mL serum. After 30 minutes of clotting, promptly centrifuge.</p>
Methodology
 
Stability
Room Temperature Unacceptable, Refrigerated 4 days, Frozen 14 days
Reference Range
By Report*
Turnaround
1-3 DAYS -- PERFORMED MON, WED, THURS, FRI
Clinical Use
<p>Methylmalonic acid is a very sensitive indicator of Vitamin B12 deficiency at the tissue level. Mildly elevated levels (0.4-1.0 umol/L) are seen in patients with decreased renal function. Extremely high levels (&gt;20 umol/L) are indicative of methylmalonic acidemia, an inborn error of metabolism disorder.</p>
Test Code
MMA/A
 

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