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Title | NEUTROPHIL CYTOPLASMIC ANTIBODY (ANCA, Vasculitides) |
Specimen Requirement | <p>1 SST/2.0 mL serum. After 30 minutes of clotting, promptly centrifuge and refrigerate serum. (Includes evaluation for P-ANCA, C-ANCA and atypical P-ANCA)</p> |
Methodology | |
Stability | Room Temp 7 days; Refrigerated: 14 days; Frozen 30 days |
Reference Range | By Report* |
Turnaround | Within 3 days/Set Up: Tues-Sat a.m. |
Clinical Use | <p>C-ANCA are present in 84-100% of patients with generalized Wegener granulomatosis (WG). C-ANCA-positive sera containing PR-3 Abs are 80% sensitive and 97% specific for WG. Positive ANCA results obtained in patients with other types of vasculitis typically give a PANCA pattern and are usually associated with autoantibodies to myeloperoxidase (MPO).</p> |
Test Code | ANCAQ |
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